Senexin B
Senexin B (SNX2-1-165) is a highly potent, selective and orally available CDK8/CDK19 inhibitor with IC50 of 24-50 nM; exhibits selectivity for CDK8 and CDK19 with Kd of 140 nM and 80 nM, respectively; significantly suppresses tumor growth in ER-positive breast cancer xenografts.
Product Specifications
CAS Number
1449228-40-3
Product Name Alternative
SNX2-1-165
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (C1=CC2=CC=C (CCNC3=C4C (C=CC (C#N) =C4) =NC=N3) C=C2C=C1) N5CCN (C) CC5
Molecular Formula
C27H26N6O
Molecular Weight
450.53
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4- ((2- (6- (4-Methylpiperazine-1-carbonyl) naphthalen-2-yl) ethyl) amino) quinazoline-6-carbonitrile
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS9713859-01 48 Tests
Human Troponin C, Skeletal Muscle (TNNC2) ELISA Kit
Sign In for Pricing
View Details MBS9713859-02 96 Tests
Human Troponin C, Skeletal Muscle (TNNC2) ELISA Kit
Sign In for Pricing
View Details MBS9713859-03 5x 96 Tests
Human Troponin C, Skeletal Muscle (TNNC2) ELISA Kit
Sign In for Pricing
View Details 
K0114803 1.0 µg DNA
ARHGAP6 sgRNA CRISPR Lentivector (Human) (Target 2)
Sign In for Pricing
View Details