Gastrodin

Gastrodin, an anti-inflammatory polyphenol extracted from Chinese natural herbal Gastrodia elata Blume., benefits neurodegenerative diseases. Extracted from Orchids Gastrodia; Suitability:Water, methanol, ethanol; Store the product in sealed, cool and dry condition. (In Vitro) :Gastrodin treatment reduces the mRNA expression levels of TNF-α and iNOS in the retinas of acute ocular hypertension. (In Vivo) :Intraperitoneal injection with Gastrodin 10 mg/kg or 50 mg/kg once daily for 15 d significantly inhibits the loss of retinal ganglion cells (RGCs) because of acute ocular hypertension (AOH) damage. 2 wk after AOH, the number of Iba1 positive retinal microglia obviously reduces to 231.3±54.3 cells/mm2 and 201.9±43.1 cells/mm2 in the rats intraperitoneally injected with Gastrodin at 10 mg/kg and 50 mg/kg, respectively.