Naringenin
Naringenin is a bioflavonoid drug potentially for the treatment of HCV infection. has antioxidant and chelating effects in the liver. Naringenin significantly suppressed UVB-induced extracellular signal-regulated kinase 2 (ERK2) activity and subsequently attenuated UVB-induced phosphorylation of p90 (RSK) by competitively binding with ATP. Naringenin exerts potent anti-photoaging effects by suppressing ERK2 activity and decreasing FRA1 stability, followed by down-regulation of AP-1 transactivation and MMP-1 expression. Naringenin blocks TGF-β1 trafficking from the trans-Golgi network by suppressing PKC activity, resulting in a reduction of TGF-β1 secretion from breast cancer cells.
Product Specifications
CAS Number
480-41-1
Product Name Alternative
Naringenin | NSC 11855 | NSC-11855 | NSC11855
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 50 mg/mL; 183.65 mM
Smiles
C1[C@H] (Oc2cc (cc (c2C1=O) O) O) c1ccc (cc1) O
Molecular Formula
C15H12O5
Molecular Weight
272.26
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(S) -5,7-dihydroxy-2- (4-hydroxyphenyl) chroman-4-one
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