Saprisartan
Saprisartan is an AT1 receptor antagonist. It is based on medications of losartan's prototypical chemical structure. The mode of (functional) AT1 receptor antagonism has been characterized as insurmountable/noncompetitive for saprisartan. It is very likely that slow dissociation kinetics from the AT1 receptor underlie insurmountable antagonism.
Product Specifications
CAS Number
146623-69-0
Purity
>98% (HPLC)
Smiles
CCC1=NC (=C (N1CC2=CC3=C (C=C2) OC (=C3Br) C4=CC=CC=C4NS (=O) (=O) C (F) (F) F) C (=O) N) C5CC5
Molecular Formula
C25H22BrF3N4O4S
Molecular Weight
611.431
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1-[[3-Bromo-2-[2-[[ (trifluoromethyl) sulfonyl]amino]phenyl]-5-benzofuranyl]methyl]-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxamide
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