PGS-IN-1
PGS-IN-1 is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM) . (In Vitro) :PGS-IN-1 is the trans isomer of the synthesized α-benzulidene-γ-butyrolactone. PGS-IN-1 exhibits potent anti-inflammatory and PGS inhibitory activity with IC50 of 0.28 μM. PGS-IN-1 also shows potent inhibitory activity against 5-lipoxygenase with IC50 of 1.05 μM.
Product Specifications
CAS Number
102271-49-8
Product Name Alternative
KME-4
Purity
>98% (HPLC)
Smiles
CC (C) (C) c1cc (\C=C2/CCOC2=O) cc (c1O) C (C) (C) C
Molecular Formula
C19H26O3
Molecular Weight
302.414
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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