AGX51
AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death. (In Vitro) :AGX51 inhibits the Id1-E47 interaction. AGX51 is well-tolerated in mice and phenocopies the genetic loss of Id expression in AMD and ROP models by inhibiting retinal neovascularization. AGX51 may have utility in the management of multiple diseases.
Product Specifications
CAS Number
330834-54-3
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (231.74 mM)
Smiles
CCC (=O) N (CCC (c1ccc2OCOc2c1) c1ccccc1OC) Cc1ccccc1
Molecular Formula
C27H29NO4
Molecular Weight
431.532
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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