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Aspoxicillin

Aspoxicillin is a broad-spectrum antimicrobial agent against Actinobacillus pleuropneumoniae with of MIC90 < or = 0.05 μg/ml. (In Vitro) :Aspoxicillin induces postantibiotic effects against Staphylococcus aureus Smith of 1.7 h in vitro .Growth suppression by sub-MICs of aspoxicillin was examined in vitro using either previously unexposed bacterial cells or cells which had been pre-exposed to twice the MIC of aspoxicillin for 2 h . (In Vivo) :Aspoxicillin has a long half-life in mouse serum of 55 minutes. Aspoxicillin induces PAEs against Staphylococcus aureus Smith of 5.2 h in vivo in a thigh infection model in neutropenic mice .

Product Specifications

CAS Number

63358-49-6

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

In Vitro: H2O : 25 mg/mL (50.66 mM)

Smiles

[H][C@]12SC (C) (C) [C@@H] (N1C (=O) [C@H]2N ([C@@H] (C (N) =O) c1ccc (O) cc1) C (=O) [C@@H] (CC (N) =O) NC) C (O) =O

Molecular Formula

C21H27N5O7S

Molecular Weight

493.54

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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