Aspoxicillin
Aspoxicillin is a broad-spectrum antimicrobial agent against Actinobacillus pleuropneumoniae with of MIC90 < or = 0.05 μg/ml. (In Vitro) :Aspoxicillin induces postantibiotic effects against Staphylococcus aureus Smith of 1.7 h in vitro .Growth suppression by sub-MICs of aspoxicillin was examined in vitro using either previously unexposed bacterial cells or cells which had been pre-exposed to twice the MIC of aspoxicillin for 2 h . (In Vivo) :Aspoxicillin has a long half-life in mouse serum of 55 minutes. Aspoxicillin induces PAEs against Staphylococcus aureus Smith of 5.2 h in vivo in a thigh infection model in neutropenic mice .
Product Specifications
CAS Number
63358-49-6
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
In Vitro: H2O : 25 mg/mL (50.66 mM)
Smiles
[H][C@]12SC (C) (C) [C@@H] (N1C (=O) [C@H]2N ([C@@H] (C (N) =O) c1ccc (O) cc1) C (=O) [C@@H] (CC (N) =O) NC) C (O) =O
Molecular Formula
C21H27N5O7S
Molecular Weight
493.54
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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