Ca2+ channel agonist 1
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction. (In Vitro) :Ca2+ channel agonist 1 (Compound 13d) exhibits a ca. 2-fold increased agonism and a 22-fold decreased cdk2 kinase activity versus the standard, (R) -roscovitine.
Product Specifications
CAS Number
1402821-24-2
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (141.06 mM)
Smiles
CCCn1cnc2c (NCc3ccccc3) nc (N[C@H] (CC) CO) nc12
Molecular Formula
C19H26N6O
Molecular Weight
354.458
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.