Calmidazolium chloride
Calmidazolium chloride is a calmodulin (CaMK) antagonist (Kd = 3 nM), antagonizing CaM-dependent phosphodiesterase (IC50 = 0.15 μM) and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase (IC50 = 0.35 μM) . Calmidazolium chloride also induces apoptosis in certain cancer cell lines. (In Vitro) :Calmidazolium chloride inhibits growth of mouse F9 ECCs (IC50 = 8.18 μM) and E14 ESCs (IC50 = 12.69 μM) .
Product Specifications
CAS Number
57265-65-3
Product Name Alternative
R 24571
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (145.41 mM)
Smiles
[Cl-].Clc1ccc (cc1) C (c1ccc (Cl) cc1) [n+]1ccn (CC (OCc2ccc (Cl) cc2Cl) c2ccc (Cl) cc2Cl) c1
Molecular Formula
C31H23Cl7N2O
Molecular Weight
687.69
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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