NRC-2694
NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR) . It has anti-cancer and anti-proliferative properties. (In Vitro) :NRC-2694 (80 ng) induce comparable inhibition of EGFR expression. (In Vivo) :NRC-2694 (10 mg/kg) regresses the tumor in mice. The maximum tolerated dose of NRC-2694 in male and female mice is 2000 mg/kg (p.o.), in toxicity studies .
Product Specifications
CAS Number
936446-61-6
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (597.39 mM)
Smiles
COc1cc2ncnc (Nc3cccc (c3) C#C) c2cc1OCCCN1CCOCC1
Molecular Formula
C24H26N4O3
Molecular Weight
418.497
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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