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NRC-2694

NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR) . It has anti-cancer and anti-proliferative properties. (In Vitro) :NRC-2694 (80 ng) induce comparable inhibition of EGFR expression. (In Vivo) :NRC-2694 (10 mg/kg) regresses the tumor in mice. The maximum tolerated dose of NRC-2694 in male and female mice is 2000 mg/kg (p.o.), in toxicity studies .

Product Specifications

CAS Number

936446-61-6

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 250 mg/mL (597.39 mM)

Smiles

COc1cc2ncnc (Nc3cccc (c3) C#C) c2cc1OCCCN1CCOCC1

Molecular Formula

C24H26N4O3

Molecular Weight

418.497

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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