Tebipenem
Tebipenem is an orally available carbapenem antibiotic. It displays broad-spectrum activity against Gram-positive and -negative bacteria. (In Vitro) :Tebipenem shows potent activity against B. pseudomallei (MIC50 and MIC90: both 2 mg/L) . Tebipenem displays slow tight-binding inhibition at low micromolar concentrations versus the chromogenic substrate nitrocefin (apparent Km and kcat: 0.8 μM and 0.03 min-1, respectively) . Tebipenem shows good activity against S. pneumoniae, with the MIC range of ≤0.25 μg/mL in all of the S. pneumoniae isolates .
Product Specifications
CAS Number
161715-21-5
Product Name Alternative
LJC 11036
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 33.33 mg/mL (86.91 mM)
Smiles
C[C@@H] (O) [C@@H]1[C@H]2[C@@H] (C) C (SC3CN (C3) C3=NCCS3) =C (N2C1=O) C (O) =O
Molecular Formula
C16H21N3O4S2
Molecular Weight
383.48
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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