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Tebipenem

Tebipenem is an orally available carbapenem antibiotic. It displays broad-spectrum activity against Gram-positive and -negative bacteria. (In Vitro) :Tebipenem shows potent activity against B. pseudomallei (MIC50 and MIC90: both 2 mg/L) . Tebipenem displays slow tight-binding inhibition at low micromolar concentrations versus the chromogenic substrate nitrocefin (apparent Km and kcat: 0.8 μM and 0.03 min-1, respectively) . Tebipenem shows good activity against S. pneumoniae, with the MIC range of ≤0.25 μg/mL in all of the S. pneumoniae isolates .

Product Specifications

CAS Number

161715-21-5

Product Name Alternative

LJC 11036

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 33.33 mg/mL (86.91 mM)

Smiles

C[C@@H] (O) [C@@H]1[C@H]2[C@@H] (C) C (SC3CN (C3) C3=NCCS3) =C (N2C1=O) C (O) =O

Molecular Formula

C16H21N3O4S2

Molecular Weight

383.48

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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