4-Hydroxybenzylamine

4-HOBA is a less reactive isomer of 2-HOBA as well as related compounds in a mouse model of hypertension. (In Vivo) :4-HOBA attenuated the left ventricular (LV) and lung IsoLGs in mice after TAC. 4-HOBA attenuated TAC-induced LV hypertrophy, heart failure, and the increase of lung weight in mice, and also improved TAC-induced LV dysfunction. Moreover, 4-HOBA effectively attenuated LV cardiomyocyte hypertrophy, lung inflammation, lung fibrosis.