Ataciguat
Ataciguat (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator. (In Vitro) :Ataciguat induces the relaxation in aortic rings or coronary rings. In the presence of nitric oxide synthase (NOS) inhibitor, the endothelium effect was abolished to DETA-NO or ataciguat, in both vessels. Ataciguat was able to induce NO production in HUVECs cells. In the presence of NOS inhibitor, the NO production induced by ataciguat was abolished.
Product Specifications
CAS Number
254877-67-3
Product Name Alternative
HMR-1766
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (173.46 mM)
Smiles
Clc1ccc (s1) S (=O) (=O) Nc1ccc (Cl) cc1C (=O) Nc1ccc (cc1) S (=O) (=O) N1CCOCC1
Molecular Formula
C21H19Cl2N3O6S3
Molecular Weight
576.48
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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