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Carbamazepine 10,11-epoxide

Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine.It is formed from carbamazepine by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes prepared from HepG2 cells expressing CYP3A4 or CYP2C8, respectively.Carbamazepine 10,11-epoxide has anticonvulsant activity against maximal electroshock-induced seizures in mice.2It has been found in wastewater effluent.

Product Specifications

CAS Number

36507-30-9

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 125 mg/mL (495.50 mM)

Smiles

NC (=O) N1c2ccccc2C2OC2c2ccccc12

Molecular Formula

C15H12N2O2

Molecular Weight

252.273

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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