Carbamazepine 10,11-epoxide
Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine.It is formed from carbamazepine by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes prepared from HepG2 cells expressing CYP3A4 or CYP2C8, respectively.Carbamazepine 10,11-epoxide has anticonvulsant activity against maximal electroshock-induced seizures in mice.2It has been found in wastewater effluent.
Product Specifications
CAS Number
36507-30-9
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 125 mg/mL (495.50 mM)
Smiles
NC (=O) N1c2ccccc2C2OC2c2ccccc12
Molecular Formula
C15H12N2O2
Molecular Weight
252.273
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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