Sodium Camptothecin
Sodium Camptothecin is a plant alkaloid, with antitumor activity. Sodium Camptothecin is a reversible inhibitor of RNA synthesis. Sodium Camptothecin is an effective inhibitor of adenovirus replication. Sodium Camptothecin inhibits DNA synthesis and causes breaks in intracellular preformed viral DNA . (In Vitro) :Sodium Camptothecin (5 μM; 10 min) causes a severe inhibition of heterogeneously sedimenting nuclear RNA (HnRNA) synthesis . Sodium Camptothecin also blocks a specific step in the processing of ribosomal precursor RNA, allowing the conversion of 45S RNA to 32S RNA, but inhibiting the conversion of 32S RNA to 28S RNA .
Product Specifications
CAS Number
25387-67-1
Purity
>98% (HPLC)
Solubility
In Vitro: H2O : 50 mg/mL (128.75 mM)
Smiles
[Na+].CCC (O) (C ([O-]) =O) c1cc2-c3nc4ccccc4cc3Cn2c (=O) c1CO
Molecular Formula
C20H17N2NaO5
Molecular Weight
388.355
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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