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Thalidomide 4-fluoride

Thalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.

Product Specifications

CAS Number

835616-60-9

Product Name Alternative

E3 ligase Ligand 4

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 300 mg/mL (1086.09 mM)

Smiles

Fc1cccc2C (=O) N (C3CCC (=O) NC3=O) C (=O) c12

Molecular Formula

C13H9FN2O4

Molecular Weight

276.223

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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