VU6015929
VU6015929 is an inhibitor of active dual discoidin domain receptor 1/2 (DDR1/2) (IC50s of 4.67 nM and 7.39 nM, respectively) . (In Vitro) :VU6015929 potently blocks collagen-induced DDR1 activation and collagen-IV production, suggesting DDR1 inhibition as an exciting target for antifibrotic therapy.
Product Specifications
CAS Number
2442597-56-8
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (515.01 mM)
Smiles
Cn1ccc (n1) -c1cncc (CNc2cc (ccc2F) C (=O) Nc2cccc (OC (F) (F) F) c2) c1
Molecular Formula
C24H19F4N5O2
Molecular Weight
485.443
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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