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VU6015929

VU6015929 is an inhibitor of active dual discoidin domain receptor 1/2 (DDR1/2) (IC50s of 4.67 nM and 7.39 nM, respectively) . (In Vitro) :VU6015929 potently blocks collagen-induced DDR1 activation and collagen-IV production, suggesting DDR1 inhibition as an exciting target for antifibrotic therapy.

Product Specifications

CAS Number

2442597-56-8

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 250 mg/mL (515.01 mM)

Smiles

Cn1ccc (n1) -c1cncc (CNc2cc (ccc2F) C (=O) Nc2cccc (OC (F) (F) F) c2) c1

Molecular Formula

C24H19F4N5O2

Molecular Weight

485.443

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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