Ensitrelvir
Ensitrelvir. (In Vitro) :The EC50 values for SARS-CoV and MERS-CoV were 0.21 and 1.4 μM respectively. In a cytopathic effect (cpe) -inhibition assay of SARS-CoV-2 infected VeroE6/TMPRSS2 cells, Ensitrelvir shows the EC50 values are approximately 0.4 μM for both wild-type virus and Alpha, Beta, Gamma and Delta variants. (In Vivo) :Ensitrelvir inhibits intrapulmonary replication of SARS-CoV-2 in mice in a dose-dependent manner.
Product Specifications
CAS Number
2647530-73-0
Product Name Alternative
S-217622
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (94.01 mM)
Smiles
Cn1nc (cc (c (/N=C (\NC (N2Cc3nn (C) cn3) =O) /N (Cc (cc (c (F) c3) F) c3F) C2=O) c2) Cl) c2c1
Molecular Formula
C22H17ClF3N9O2
Molecular Weight
531.88
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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