DL-Tryptophan

Tryptophan containing dipeptides are interesting ingredients for functional foods as a natural prevention for hypertension with reduced side effects due to its selective inhibition of the C-domain. Low thalamic Tryptophan uptake appears to be a strong, independent predictor of long survival in patients with previous glioma treatment. (In Vitro) :Tryptophan is an essential amino acid, required for the production of serotonin. Tryptophan represents a key element for brain functioning, because of its role as a precursor for production of neurotransmitter serotonin. (In Vivo) :In clinical conditions, which involve chronic immune system activation or under cytokine therapy, lower tryptophan levels because of high catabolism of tryptophan as indicated by the kynurenine to tryptophan ratio are common and often associate with depressive mood.