STX-478
STX-478 is an allosteric PI3Kα inhibitor that selectively targets prevalent PI3Kα helical- and kinase-domain mutant tumors. STX-478 provides robust efficacy while avoiding the metabolic dysfunction associated with the nonselective inhibitor alpelisib.
Product Specifications
CAS Number
2883540-92-7
Purity
0.98
Smiles
NC1=NC=C (C=N1) NC (N[C@H] (C2=C (C3=CC (F) =CC (F) =C3O2) C) C (F) (F) F) =O
Molecular Formula
C16H12F5N5O2
Molecular Weight
401.297
Notes
For research use only.
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