BFL-1 inhibitor 4E14
BFL-1 inhibitor 4E14 (4E14) is a potent, selective, covalent BFL-1 inhibitor that disrupt BH3-binding activity with IC50 of 1.3 uM, targets a unique C55 residue in the BFL-1 groove.4E14 blocks BFL-1 suppression of BAX-mediated mitochondrial apoptosis.
Product Specifications
Field of Research
Pharmacology & Drug Discovery
Purity
>98%
Molecular Formula
C19H28N4O2S2
Molecular Weight
408.579
Notes
For research use only.
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