Nifekalant hydrochloride
Nifekalant hydrochloride is a Class III antiarrhythmic agent that selectively blocks the IKr potassium channel with an IC50 of 10 μM. It is utilized in research to study ventricular tachyarrhythmias, employing both in vitro electrophysiology assays and in vivo animal models of arrhythmia.
Product Specifications
CAS Number
130656-51-8
Product Name Alternative
Antiarrhythmic, Inhibitor, IKr, inhibit, MS551, MS-551, MS 551, KcsA, Nifekalant, Nifekalant Hydrochloride, Nifekalant hydrochloride, Potassium Channel, potassium channel, PotassiumChannel, tachyarrhythmias, ventricular
Field of Research
Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.26 mM) ; DMSO:9 mg/mL (20.37 mM)
Smiles
Cl.Cn1c (NCCN (CCO) CCCc2ccc (cc2) [N+] ([O-]) =O) cc (=O) n (C) c1=O
Molecular Formula
C19H28ClN5O5
Molecular Weight
441.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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