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Nifekalant hydrochloride

Nifekalant hydrochloride is a Class III antiarrhythmic agent that selectively blocks the IKr potassium channel with an IC50 of 10 μM. It is utilized in research to study ventricular tachyarrhythmias, employing both in vitro electrophysiology assays and in vivo animal models of arrhythmia.

Product Specifications

CAS Number

130656-51-8

Product Name Alternative

Antiarrhythmic, Inhibitor, IKr, inhibit, MS551, MS-551, MS 551, KcsA, Nifekalant, Nifekalant Hydrochloride, Nifekalant hydrochloride, Potassium Channel, potassium channel, PotassiumChannel, tachyarrhythmias, ventricular

Field of Research

Pharmacology & Drug Discovery

Purity

98.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.26 mM) ; DMSO:9 mg/mL (20.37 mM)

Smiles

Cl.Cn1c (NCCN (CCO) CCCc2ccc (cc2) [N+] ([O-]) =O) cc (=O) n (C) c1=O

Molecular Formula

C19H28ClN5O5

Molecular Weight

441.91

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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