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7-Methylguanine

7-Methylguanine is a natural metabolite and competitive PARP1 inhibitor (Ki=61 μM) that disrupts NAD+ binding. It exhibits anticancer properties in research models and serves as a chemical probe for studying protein-DNA interactions in both cellular and biochemical assays.

Product Specifications

CAS Number

578-76-7

Product Name Alternative

7Methylguanine, 7-Methylguanine, 7 Methylguanine, Human Endogenous Metabolite, N7-Methylguanine

Field of Research

Epigenetics & Chromatin, Metabolism Research, Molecular Biology

Purity

99.99% (May vary between batches)

Solubility

1M NaOH:80 mg/mL (484.41 mM) ; H2O:3.3 mg/mL (19.98 mM)

Smiles

O=C1N=C (N) NC=2N=CN (C12) C

Molecular Formula

C6H7N5O

Molecular Weight

165.15

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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