7-Methylguanine
7-Methylguanine is a natural metabolite and competitive PARP1 inhibitor (Ki=61 μM) that disrupts NAD+ binding. It exhibits anticancer properties in research models and serves as a chemical probe for studying protein-DNA interactions in both cellular and biochemical assays.
Product Specifications
CAS Number
578-76-7
Product Name Alternative
7Methylguanine, 7-Methylguanine, 7 Methylguanine, Human Endogenous Metabolite, N7-Methylguanine
Field of Research
Epigenetics & Chromatin, Metabolism Research, Molecular Biology
Purity
99.99% (May vary between batches)
Solubility
1M NaOH:80 mg/mL (484.41 mM) ; H2O:3.3 mg/mL (19.98 mM)
Smiles
O=C1N=C (N) NC=2N=CN (C12) C
Molecular Formula
C6H7N5O
Molecular Weight
165.15
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6235017-01 0.1 mL
RLIM (RING Finger LIM Domain-binding Protein, R-LIM, E3 Ubiquitin-protein Ligase RLIM, LIM Domain-interacting RING Finger Protein, RING Finger Protein 12, RNF12, Renal Carcinoma Antigen NY-REN-43) (MaxLight 750)
Sign In for Pricing
View Details MBS6235017-02 5x 0.1 mL
RLIM (RING Finger LIM Domain-binding Protein, R-LIM, E3 Ubiquitin-protein Ligase RLIM, LIM Domain-interacting RING Finger Protein, RING Finger Protein 12, RNF12, Renal Carcinoma Antigen NY-REN-43) (MaxLight 750)
Sign In for Pricing
View Details 
035929-ML750 100 µL
GATAD2B, NT (GATAD2B, KIAA1150, Transcriptional repressor p66-beta, GATA zinc finger domain-containing protein 2B, p66/p68) (MaxLight 750) discontinued
Sign In for Pricing
View Details