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Gefitinib hydrochloride

Gefitinib hydrochloride is a potent and selective oral EGFR tyrosine kinase inhibitor. It is widely used in oncology research to study its antitumor effects, including the inhibition of EGF-driven cell proliferation, induction of autophagy, and modulation of inflammation and fibrosis in both cellular and animal models.

Product Specifications

CAS Number

184475-55-6

Product Name Alternative

ZD1839 hydrochloride, ZD-1839 hydrochloride, EGFR

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.80% (May vary between batches)

Solubility

DMSO:< 0.1 mg/mL (insoluble) ; H2O:4 mg/mL (8.28 mM)

Smiles

Cl.FC1=CC=C (C=C1Cl) NC=2N=CN=C3C=C (OC) C (OCCCN4CCOCC4) =CC32

Molecular Formula

C22H25Cl2FN4O3

Molecular Weight

483.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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