Aphidicolin
Aphidicolin is a fungal-derived antibiotic that potently inhibits eukaryotic DNA polymerases α and δ, blocking DNA replication and herpes simplex virus proliferation. It is widely used in cell cycle synchronization studies in vitro and has been shown to enhance apoptosis in combination therapies in leukemia cell line research.
Product Specifications
CAS Number
38966-21-1
Field of Research
Cell Biology
Purity
>98%
Bioactivity
DNA polymerase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 1 mg/ml) .
Smiles
[H][C@]12C[C@]3 ([H]) C[C@]1 (CC[C@]3 (O) CO) [C@@]1 (C) CC[C@@H] (O) [C@@] (C) (CO) [C@]1 ([H]) CC2
Molecular Formula
C20H34O4
Molecular Weight
338.48
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(3R,4R,4aR,6aS,8R,9R,11aS,11bS) -Tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-8,11a-methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol
Available Sizes
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