DBCO-Maleimide
DBCO-Maleimide (DBCO-MAL) is a heterobifunctional, non-cleavable linker used in constructing antibody-drug conjugates (ADCs) . It enables stable, site-specific conjugation via copper-free click chemistry and maleimide-thiol coupling, facilitating ADC development for both in vitro and in vivo cancer research applications.
Product Specifications
CAS Number
1395786-30-7
Product Name Alternative
Cleavable, ADCLinker, ADC Linker, DBCO Maleimide, DBCO-MAL, DBCOMaleimide, DBCO-Maleimide
Purity
97.01% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.72 mM) ; DMSO:80 mg/mL (187.16 mM)
Smiles
O=C1C=CC (=O) N1CCC (=O) NCCC (=O) N2C=3C=CC=CC3C#CC=4C=CC=CC4C2
Molecular Formula
C25H21N3O4
Molecular Weight
427.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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