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DBCO-Maleimide

DBCO-Maleimide (DBCO-MAL) is a heterobifunctional, non-cleavable linker used in constructing antibody-drug conjugates (ADCs) . It enables stable, site-specific conjugation via copper-free click chemistry and maleimide-thiol coupling, facilitating ADC development for both in vitro and in vivo cancer research applications.

Product Specifications

CAS Number

1395786-30-7

Product Name Alternative

Cleavable, ADCLinker, ADC Linker, DBCO Maleimide, DBCO-MAL, DBCOMaleimide, DBCO-Maleimide

Purity

97.01% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.72 mM) ; DMSO:80 mg/mL (187.16 mM)

Smiles

O=C1C=CC (=O) N1CCC (=O) NCCC (=O) N2C=3C=CC=CC3C#CC=4C=CC=CC4C2

Molecular Formula

C25H21N3O4

Molecular Weight

427.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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