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M-PEG4-Br

M-PEG4-Br is a cleavable linker utilized in constructing antibody-drug conjugates (ADCs) like those employing Trastuzumab and MMAE. Its distal placement from the payload modulates conjugate hydrophilicity and binding properties, which are critical parameters evaluated in both in vitro cytotoxicity assays and in vivo efficacy studies for targeted cancer therapy.

Product Specifications

CAS Number

110429-45-3

Field of Research

Pharmacology & Drug Discovery

Smiles

COCCOCCOCCOCCBr

Molecular Formula

C9H19BrO4

Molecular Weight

271.15

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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