Propargyl-PEG1-acid
Propargyl-PEG1-acid is a versatile linker used to construct PROTAC degraders, such as Ibrutinib-based BTK-CRBN PROTACs. At 10 μM, the resulting PROTAC 5 induces the degradation of BTK and additionally targets CSK, LYN, and LAT2, making it a valuable tool for targeted protein degradation research in both cellular and biochemical studies.
Product Specifications
CAS Number
55683-37-9
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
OC (=O) CCOCC#C
Molecular Formula
C6H8O3
Molecular Weight
128.13
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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