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Propargyl-PEG1-acid

Propargyl-PEG1-acid is a versatile linker used to construct PROTAC degraders, such as Ibrutinib-based BTK-CRBN PROTACs. At 10 μM, the resulting PROTAC 5 induces the degradation of BTK and additionally targets CSK, LYN, and LAT2, making it a valuable tool for targeted protein degradation research in both cellular and biochemical studies.

Product Specifications

CAS Number

55683-37-9

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Smiles

OC (=O) CCOCC#C

Molecular Formula

C6H8O3

Molecular Weight

128.13

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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