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Tetraethylene glycol

Tetraethylene glycol is a polyethylene glycol (PEG) -based linker used in constructing PROTAC molecules for targeted protein degradation. It serves as a substrate for polyethylene glycol dehydrogenase (Km = 10 mM), a feature applicable in enzymatic assays and metabolic studies for both in vitro and in vivo research applications.

Product Specifications

CAS Number

112-60-7

Product Name Alternative

Tetraethylene glycol, PROTAC Linker 18, PEGs

Field of Research

Pharmacology & Drug Discovery

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (25.74 mM) ; DMSO:80 mg/mL (411.88 mM)

Smiles

OCCOCCOCCOCCO

Molecular Formula

C8H18O5

Molecular Weight

194.23

Storage Conditions

-20°C

Notes

For research use only.

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