Tetraethylene glycol
Tetraethylene glycol is a polyethylene glycol (PEG) -based linker used in constructing PROTAC molecules for targeted protein degradation. It serves as a substrate for polyethylene glycol dehydrogenase (Km = 10 mM), a feature applicable in enzymatic assays and metabolic studies for both in vitro and in vivo research applications.
Product Specifications
CAS Number
112-60-7
Product Name Alternative
Tetraethylene glycol, PROTAC Linker 18, PEGs
Field of Research
Pharmacology & Drug Discovery
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (25.74 mM) ; DMSO:80 mg/mL (411.88 mM)
Smiles
OCCOCCOCCOCCO
Molecular Formula
C8H18O5
Molecular Weight
194.23
Storage Conditions
-20°C
Notes
For research use only.
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