TBDMS-PEG4-OH
TBDMS-PEG4-OH is a polyethylene glycol (PEG) spacer used to construct PROTAC molecules, connecting a target-binding ligand to an E3 ligase recruiter. This linker facilitates the ubiquitination and subsequent proteasomal degradation of specific proteins, a mechanism applicable in both cellular and in vivo degradation studies.
Product Specifications
CAS Number
134179-40-1
Field of Research
Pharmacology & Drug Discovery
Smiles
[Si] (OCCOCCOCCOCCO) (C (C) (C) C) (C) C
Molecular Formula
C14H32O5Si
Molecular Weight
308.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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