E3 ligase Ligand 10
E3 ligase Ligand 10 is a chemical moiety used to construct PROTAC degraders. When linked to a target-binding molecule, it recruits E3 ubiquitin ligase to induce the degradation of specific oncoproteins, a mechanism validated in both cellular and animal model studies of cancer.
Product Specifications
CAS Number
1073560-68-5
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Smiles
C (OC (N ([C@H] (C (N[C@H] (C (=O) N1[C@H] (C (N[C@@H] ([C@H] (C2=CC=CC=C2) C3=CC=CC=C3) C (O) =O) =O) CCC1) C4CCCCC4) =O) C) C) =O) C5C=6C (C=7C5=CC=CC7) =CC=CC6
Molecular Formula
C47H52N4O7
Molecular Weight
784.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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