CIAP1 ligand 1
CIAP1 ligand 1 is a proteolysis-targeting chimera (PROTAC) based on an LCL161 derivative that recruits E3 ubiquitin ligases to induce target protein degradation. It is used in prostate cancer research, particularly in conjunction with androgen receptor ligands, for developing novel degraders and has been applied in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2095244-42-9
Product Name Alternative
CIAP1, cIAP1 ligand 1, cIAP-1 ligand 1, E3 ligase Ligand 12
Field of Research
Pharmacology & Drug Discovery
Purity
98.01% (May vary between batches)
Solubility
DMSO:80 mg/mL (133.61 mM)
Smiles
C[C@H] (N (C) C (=O) OC (C) (C) C) C (=O) N[C@@H] (C1CCCCC1) C (=O) N1CCC[C@H]1c1nc (cs1) C (=O) c1cccc (O) c1
Molecular Formula
C31H42N4O6S
Molecular Weight
598.75
Storage Conditions
-20°C
Notes
For research use only.
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