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CIAP1 ligand 1

CIAP1 ligand 1 is a proteolysis-targeting chimera (PROTAC) based on an LCL161 derivative that recruits E3 ubiquitin ligases to induce target protein degradation. It is used in prostate cancer research, particularly in conjunction with androgen receptor ligands, for developing novel degraders and has been applied in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2095244-42-9

Product Name Alternative

CIAP1, cIAP1 ligand 1, cIAP-1 ligand 1, E3 ligase Ligand 12

Field of Research

Pharmacology & Drug Discovery

Purity

98.01% (May vary between batches)

Solubility

DMSO:80 mg/mL (133.61 mM)

Smiles

C[C@H] (N (C) C (=O) OC (C) (C) C) C (=O) N[C@@H] (C1CCCCC1) C (=O) N1CCC[C@H]1c1nc (cs1) C (=O) c1cccc (O) c1

Molecular Formula

C31H42N4O6S

Molecular Weight

598.75

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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