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N-Descyclopropanecarbaldehyde Olaparib

N-Descyclopropanecarbaldehyde Olaparib is a functionalized analogue of the PARP inhibitor Olaparib, incorporating a DOTA chelator. This derivative serves as a CRBN-binding ligand for constructing PROTAC molecules, such as dual-targeting EGFR/PARP degraders, and is designed for radiolabeling with F-18 or fluorophores to enable tumor visualization via PET or optical imaging in preclinical research.

Product Specifications

CAS Number

763111-47-3

Field of Research

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Smiles

Fc1ccc (Cc2n[nH]c (=O) c3ccccc23) cc1C (=O) N1CCNCC1

Molecular Formula

C20H19FN4O2

Molecular Weight

366.39

Storage Conditions

-20°C

Notes

For research use only.

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