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Biotin-PEG3-propargyl

Biotin-PEG3-propargyl is a heterobifunctional PROTAC linker that conjugates a target-binding ligand to an E3 ligase recruiter via click chemistry. This PEG-based spacer is utilized in constructing proteolysis-targeting chimeras for the selective degradation of proteins in both cellular and biochemical studies.

Product Specifications

CAS Number

1421701-68-9

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Smiles

C (CCCC (NCCOCCOCCOCC#C) =O) [C@H]1[C@@]2 ([C@] (CS1) (NC (=O) N2) [H]) [H]

Molecular Formula

C19H31N3O5S

Molecular Weight

413.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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