SC144 hydrochloride
SC144 hydrochloride is a first-in-class, orally bioavailable small molecule inhibitor targeting gp130 (IL6ST) . It blocks ligand-induced gp130 signaling, STAT3 activation, and downstream gene expression, effectively inducing apoptosis in human ovarian cancer cells in vitro. Its research applications extend to studying oncogenic signaling and therapeutic potential in various cancers.
Product Specifications
CAS Number
917497-70-2
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
Cl.O=C (NNC1=NC=2C=C (F) C=CC2N3C=CC=C13) C4=NC=CN=C4
Molecular Formula
C16H12ClFN6O
Molecular Weight
358.76
Storage Conditions
-20°C
Notes
For research use only.
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