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SIRT-IN-3

SIRT-IN-3 is a selective SIRT1 inhibitor with an IC50 of 17 μM, showing approximately 4-fold and 14-fold selectivity over SIRT2 and SIRT3, respectively. This compound is a valuable chemical probe for investigating the roles of SIRT1 in aging, metabolism, and neurodegenerative disease pathways in cellular and biochemical studies.

Product Specifications

CAS Number

1211-19-4

Field of Research

Epigenetics & Chromatin, Molecular Biology

Smiles

NC (=O) c1ccccc1Nc1ccccc1

Molecular Formula

C13H12N2O

Molecular Weight

212.25

Storage Conditions

-20°C

Notes

For research use only.

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