PI-103 Hydrochloride
PI-103 Hydrochloride is a dual PI3K/Akt and mTOR inhibitor that potently targets multiple kinases including p110 isoforms, DNA-PK, and mTOR complexes at nanomolar concentrations. It induces autophagy, mitochondrial apoptosis, and cell cycle arrest, making it a valuable tool for studying leukemia mechanisms in both cellular and animal models.
Product Specifications
CAS Number
371935-79-4
Product Name Alternative
PI 103 Hydrochloride, PI103 HCl, PI-103 Hydrochloride
Field of Research
Cell Biology, Metabolism Research, Molecular Biology, Signal Transduction
Purity
97.07% (May vary between batches)
Solubility
DMSO:3 mg/mL (7.8 mM) ; H2O:< 1 mg/mL (insoluble)
Smiles
Cl.Oc1cccc (c1) -c1nc (N2CCOCC2) c2oc3ncccc3c2n1
Molecular Formula
C19H17ClN4O3
Molecular Weight
384.82
Storage Conditions
-20°C
Notes
For research use only.
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