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3-Deazaneplanocin A

3-Deazaneplanocin A (DZNep) is a dual inhibitor of EZH2 and AHCY, promoting target degradation via the proteasome. It exhibits antifibrotic activity in hepatic, renal, and pulmonary models and has been studied in both cellular assays and animal models of fibrosis.

Product Specifications

CAS Number

102052-95-9

Product Name Alternative

3 Deazaneplanocin A, 3-Deazaneplanocin, 3Deazaneplanocin A, 3-Deazaneplanocin A, DZNep, Orthopoxvirus, Histone Methyltransferase, HistoneMethyltransferase, EZH2

Field of Research

Epigenetics & Chromatin, Infectious Disease & Virology

Purity

99.03% (May vary between batches)

Solubility

DMSO:75 mM; H2O:80 mg/mL (305.03 mM)

Smiles

O[C@H]1[C@H] (N2C=3C (N=C2) =C (N) N=CC3) C=C (CO) [C@H]1O

Molecular Formula

C12H14N4O3

Molecular Weight

262.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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