3-Deazaneplanocin A
3-Deazaneplanocin A (DZNep) is a dual inhibitor of EZH2 and AHCY, promoting target degradation via the proteasome. It exhibits antifibrotic activity in hepatic, renal, and pulmonary models and has been studied in both cellular assays and animal models of fibrosis.
Product Specifications
CAS Number
102052-95-9
Product Name Alternative
3 Deazaneplanocin A, 3-Deazaneplanocin, 3Deazaneplanocin A, 3-Deazaneplanocin A, DZNep, Orthopoxvirus, Histone Methyltransferase, HistoneMethyltransferase, EZH2
Field of Research
Epigenetics & Chromatin, Infectious Disease & Virology
Purity
99.03% (May vary between batches)
Solubility
DMSO:75 mM; H2O:80 mg/mL (305.03 mM)
Smiles
O[C@H]1[C@H] (N2C=3C (N=C2) =C (N) N=CC3) C=C (CO) [C@H]1O
Molecular Formula
C12H14N4O3
Molecular Weight
262.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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