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β-catenin-IN-3

β-catenin-IN-3 is a potent and selective small molecule inhibitor of β-catenin, binding with high affinity (K_D = 54.96 nM) to a cryptic regulatory site. It effectively suppresses the viability of β-catenin-dependent cancer cells in vitro, making it a valuable chemical probe for studying Wnt/β-catenin signaling in oncology research.

Product Specifications

CAS Number

1005288-15-2

Field of Research

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Smiles

N (C (NC=CC1=C (O) C (Br) =CC (Br) =C1) =S) C2C3C4C (C (C3) C2) CC=C4

Molecular Formula

C19H20Br2N2OS

Molecular Weight

484.25

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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