Pranlukast hemihydrate
Pranlukast hemihydrate (ONO-1078) is a potent and selective leukotriene receptor antagonist used in asthma research. It inhibits LTD4/LTE4 binding in vitro and antagonizes LTC4-induced bronchoconstriction in guinea pig models, supporting its study in airway inflammation and hyperresponsiveness.
Product Specifications
CAS Number
150821-03-7
Product Name Alternative
ONO1078 hemihydrate, ONO-1078 hemihydrate
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.28% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble) ; DMSO:20 mg/mL (40.77 mM)
Smiles
O=C1C=C (OC=2C (=CC=CC12) NC (=O) C3=CC=C (OCCCCC=4C=CC=CC4) C=C3) C5=NN=NN5.O 0.5H2O
Molecular Formula
C27H23N5O4 0.5H2O
Molecular Weight
490.52
Storage Conditions
-20°C
Notes
For research use only.
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